Bad Cholesterol Ignites Growth of Glioblastoma
Low- density lipoprotein or bad cholesterol can ignite the growth of glioblastoma, a common and most aggressive type of brain tumour, say researchers.
The treatments of this cancer still needs a lot of advancement as the survival rate after the diagnosis of the disease is near -- about 15 months.
The researchers have revealed that as bad cholesterol has been linked to glioblastoma, it will result in finding out the enhanced treatment as they know the target now.
It has been notified that up to 90% of glioblastomas have a "hyperactive signalling pathway" for cholesterol, which suggests that their cells are functioned to draw out the bad cholesterol that provokes the tumour growth.
Ohio State University radiation oncology Professor Deliang Guo stated that the growth of cancer cells relies on the cholesterol levels and if these tumour cells can be deprived with the bad cholesterol than it would restrict the cancer growth. Therefore, treatment is required to limit the link of bad cholesterol and glioblastoma.
University of California-Los Angeles Jonsson Cancer Center pathology Professor Paul Mischel stated, "It potentially offers a strategy for blocking that mechanism and causing specific tumour-cell death without significant toxicity". The findings will result in finding out a more efficient treatment to prevent deaths from this type of cancer.
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