A study published in the journal Cell reveals stem cells development as the way to treat infertility among women. The researchers from the Kyoto University claim that primordial germ cells led to production of sperms, increasing the chances of fertility among women.
The researchers had carried out an experiment on the mouse, in which they amalgamated the embryonic stem cells of mouse with the sperm precursors, called primordial germ cells (PGCs). The combining of the two produced healthy sperms, which were further made into fertilized eggs. These fertilized eggs were transferred into the female adult mice. The successful transplantation resulted in the birth of several male and female mice.
The researchers were now expecting to witness the success of the treatment among humans. As per Fertility Expert Dr. Allan Pacey, Senior Lecturer in Andrology at the University of Sheffield, "This is quite a step forward in developing a process by which sperm could be made for infertile men, perhaps by taking as a starting point a cell from their skin or from something like bone marrow”.
The researchers were further studying the vitro reconstitution of germ cell development, which involved the primitive germ of female so as to have a better understanding of the germ cell biology and also will help in improving the treatments and medication.