Gardasil, the cervical cancer vaccine, has triggered multiple sclerosis (MS) symptoms in some girls after being vaccinated.
Those who may have been prone to MS or who had a prior history of symptoms were either teenagers or women in their early 20s, doctors reported.
Symptoms began within three weeks of the girls receiving the vaccination and remained from weeks to months.
Ten cases have been reported and five were reported by St Vincent's Hospital neurologist Dr Ian Sutton in a journal in January.
The results were based on the target group of a vaccination program that began in 2007. The vaccine has been tested on more than 30, 000 women worldwide, its manufacturer CSL said.
The Therapeutic Goods Administration (TGA) last week said six million doses of Gardasil, created by scientist and former Australian of the Year Ian Frazer, had been distributed in Australia, and 1, 476 suspected adverse reactions were reported.
"The TGA is also aware of a small number of cases in which neurological symptoms, similar to those experienced in patients with a dedemyelinating disorder such as multiple sclerosis, have been reported shortly after HPV (human papillomavirus vaccination)," the regulator said, which have been investigated by an independent panel.
"In spite of reports of some neurological symptoms occurring after vaccination, when those were investigated no contributory relationship with the vaccine was determined," company spokeswoman Rachel David said.
Medical experts say the benefits of the vaccination far outweigh the risks.
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